Heart-type fatty acid-binding protein is essential for efficient brown adipose tissue fatty acid oxidation and cold tolerance*

HIGHLIGHTS

• who: Laurent Vergnes from the EXPERIMENTAL PROCEDURES Mice-Mouse embryonic stem cells containing a gene-trap insertion in the Fabp, gene (cell line XE705) were obtained from the BayGenomics gene-trap consortium (39)Chimeric mice were generated by blastocyst microinjection and then crossed with C BL/ J mice for at least four generations. The site of the gene-trap insertion within intron , of Fabp, was determined by inverse PCR. Offspring were genotyped by PCR of genomic DNA with primers specific for the wild-type Fabp, allele and for the mutant allele carrying the gene-trap insertion. FABP4 . . .
  

   

  

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