Hed, a human-engineered domain, confers a unique fc-binding activity to produce a new class of humanized antibody-like molecules

HIGHLIGHTS

• who: Zhiqiang Zhu et al. from the Department of Pathology and Lab Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA have published the research: HED, a Human-Engineered Domain, Confers a Unique Fc-Binding Activity to Produce a New Class of Humanized Antibody-like Molecules, in the Journal: (JOURNAL)
• what: The model shows that the interaction 7 of 17 location between hIgG1Fc and the HED is far from the binding_site of C1q on the Fc fragment and HED should not hinder the CDC activity mediated by the interaction of Fc with C1q . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.