HIGHLIGHTS
- who: Christiaan M. Suttorp and collaborators from the Department of Dentistry-Orthodontics and Craniofacial Biology, Radboud University Medical Center, GA Nijmegen, The Netherlands have published the research work: Heme Oxygenase Protects against Placental Vascular Inflammation and Abortion by the Alarmin Heme in Mice, in the Journal: (JOURNAL) of 20/08/2012
- what: This study demonstrated that mimicking intrauterine hemorrhage/hematoma by i.p. administration of the endogenous "alarmin" heme, at Day E12 in pregnant mice, causes abortion/resorption in a dose-dependent fashion. The authors show here that HO-activity is also crucial for protecting . . .
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