Heparan sulfate facilitates binding of hifn to its cell-surface receptor hifngr1

HIGHLIGHTS

  • who: Elisaveta Miladinova et al. from the Faculty of Physics, University "StKliment Ohridski", James Bourchier Blvd, have published the paper: Heparan Sulfate Facilitates Binding of hIFN to Its Cell-Surface Receptor hIFNGR1, in the Journal: (JOURNAL)
  • what: The authors report the studies by means of molecular dynamics (MD) simulations and indirect in_vitro experiments on the interaction of hIFNγ with hIFNGR1 in different scenarios, probing the viability of a third-party involvement in the complex-formation process.
  • how: For this analysis only the last 150 ns of each trajectory were employed. The obtained results . . .

     

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