Heparanase modulates the prognosis and development of braf v600e-mutant colorectal cancer by regulating akt/p27kip1/cyclin e2 pathway

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  • who: Mengling Liu from the Fudan University have published the Article: Heparanase modulates the prognosis and development of BRAF V600E-mutant colorectal cancer by regulating AKT/p27Kip1/Cyclin E2 pathway, in the Journal: (JOURNAL) of 19/08/2022
  • what: Analysis in this study showed that heparanase (HPSE) is one of the significantly differentially expressed genes (DEGs) in BRAF V600E-mutant CRC patients. This investigation focused on the role and mechanism of HPSE in BRAF V600E-mutant CRC. In the present study, by analyzing the transcriptome sequencing data of two public datasets, HPSE was revealed to . . .

     

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