Heparin activation of protein z-dependent protease inhibitor (zpi) allosterically blocks protein z activation through an extended heparin-binding site

HIGHLIGHTS

• who: Xin Huang from the Xin Huang1, *, Richard Swanson2, and Steven TOlson, From the Department of Pharmacology and Regenerative Medicine and Department of Periodontics, University of Illinois Chicago, Chicago, Illinois, USA Edited by George DeMartino have published the research work: Heparin activation of protein Z-dependent protease inhibitor (ZPI) allosterically blocks protein Z activation through an extended heparin-binding site, in the Journal: (JOURNAL) of March/12,/2022
• what: The authors show that heparin binding to ZPI antagonizes PZ binding to and activation of ZPI.

SUMMARY

Virtual docking of heparin to . . .

 



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