Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (l444r) of heparin cofactor ii*

HIGHLIGHTS

  • who: Jin-Hua Han from the Materials-Human a-thrombin was prepared as described previously (8) or purchased from Hematologic Technologies (Essex Junction, VT)Thrombin was labeled with Na I (ICN Biomedicals, Costa Mesa, CA) by the chloramine-T method (8) to attain a specific radioactivity of have published the Article: Heparin Facilitates Dissociation of Complexes between Thrombin and a Reactive Site Mutant (L444R) of Heparin Cofactor II*, in the Journal: (JOURNAL) of June/26,/1996
  • what: The authors demonstrate differences in the stability of the thrombin-rHCII and thrombinrHCII(L444R) complexes.

SUMMARY . . .

 

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