Hepatic non-parenchymal s100a9-tlr4-mtorc1 axis normalizes diabetic ketogenesis

HIGHLIGHTS

  • who: Gloria Ursino from the University of Geneva, Geneva, Switzerland have published the paper: Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show pre-clinical and observational clinical data indicating that recombinant S100A9 is a putative investigational drug displaying safety and efficacy profiles owning therapeutic potential. To further evaluate the translational significance of the findings , the authors performed an observational clinical study aimed at gathering plasmatic S100A9 content in patients with decompensated diabetes and healthy controls. As indicated in Fig 7K and based . . .

     

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