Hepatic oleate regulates insulin-like growth factor-binding protein 1 partially through the mtorc1-fgf21 axis during high-carbohydrate feeding

HIGHLIGHTS

• who: Lucas M. Ou2019Neill and collaborators from the Department of Biochemistry, University of Wisconsin-Madison, Babcock Drive, Madison, WI, USA have published the Article: Hepatic Oleate Regulates Insulin-like Growth Factor-Binding Protein 1 Partially through the mTORC1-FGF21 Axis during High-Carbohydrate Feeding, in the Journal: (JOURNAL) of 21/Oct/2022
• what: The authors show that insulin-like growth factor-binding protein 1 (IGFBP1) a hepatokine that has been reported to enhance insulin signaling is significantly elevated in the liver and plasma of GKO and LKO mice fed a low-fat high-carbohydrate diet . . .
  

   

  

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