Hepatic organoid-based high-content imaging boosts evaluation of stereoisomerism-dependent hepatotoxicity of stilbenes in herbal medicines

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  • who: Petr Pavek et al. from the Charles University, Czechia Academy of Sciences, China have published the article: Hepatic Organoid-Based High-Content Imaging Boosts Evaluation of Stereoisomerism-Dependent Hepatotoxicity of Stilbenes in Herbal Medicines, in the Journal: (JOURNAL)
  • what: As hepatotoxicity is one of the major reasons for developmental failures and withdrawal of new drugs, the development of evaluating models is needed to assess drugs and study the possible mechanisms of drug-induced liver injury (DILI) (Njoku 2014; Shehu et_al, 2017). The authors tried to assess the possible hepatotoxic differences between a pair of . . .

     

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