HIGHLIGHTS
- who: Pei-Yi Su from the (UNIVERSITY) have published the paper: Hepatitis B virus virion secretion is a CRM1-spike-mediated late event, in the Journal: (JOURNAL)
- what: The authors report here that the tip of spike of_(HBc) particles (capsids) contains a complex sensor for of both virions and naked is closely associated with nuclear export in a CRM1-dependent manner. The authors report here an unexpected finding that CRM1 plays a crucial role in HBV virion secretion.
- how: The authors used site-directed mutagenesis at the NES as well as treatment . . .
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