HIGHLIGHTS
- who: Jinrui Dong and colleagues from the Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London , NN, UK have published the article: Hepatocyte Specific gp130 Signalling Underlies APAP Induced Liver Injury, in the Journal: (JOURNAL) of 23/06/2022
- what: The authors show here that aggregate gp130 signaling (i.e., the integration of the effects of all ligands acting via gp130) in injured adult hepatocytes promotes APAP-induced liver damage and inhibits liver regeneration.
- how: The experiments building on previous . . .
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