Her2-displaying m13 bacteriophages induce therapeutic immunity against breast cancer

HIGHLIGHTS

  • who: Junbiao Wang and collaborators from the School of Biosciences and Veterinary Medicine, Biology Division, University of Camerino, via Gentile III da Varano, Camerino, Italy have published the Article: HER2-Displaying M13 Bacteriophages induce Therapeutic Immunity against Breast Cancer, in the Journal: (JOURNAL)
  • what: The authors demonstrate that both preventive and vaccination with the extracellular (EC) and transmembrane (TM) domains of human or its u220616HER2 splice variant on their surface (ECTM and u220616ECTM phages) delayed mammary tumor onset and reduced tumor growth rate and multiplicity in u220616HER2 transgenic mice which are tolerant to human u220616HER2 . . .

     

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