Her2-displaying m13 bacteriophages induce therapeutic immunity against breast cancer

HIGHLIGHTS

  • who: Junbiao Wang and colleagues from the School of Biosciences and Veterinary Medicine, Biology Division, University of Camerino, via Gentile III da Varano, Camerino, Italy have published the research work: HER2-Displaying M13 Bacteriophages induce Therapeutic Immunity against Breast Cancer, in the Journal: (JOURNAL)
  • what: The authors demonstrate that both preventive and vaccination with the extracellular (EC) and transmembrane (TM) domains of human or its ∆16HER2 splice variant on their surface (ECTM and ∆16ECTM phages) delayed mammary tumor onset and reduced tumor growth rate and multiplicity in ∆16HER2 transgenic mice which are tolerant to human . . .

     

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