Hereditable variants of classical protein tyrosine phosphatase genes: will they prove innocent or guilty?

HIGHLIGHTS

  • who: January et al. from the New York University, United States have published the Article: Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?, in the Journal: (JOURNAL)
  • what: The authors present a comprehensive overview of currently documented sequence variants in the classical subset of PTP genes, and discuss existing or suspected links with hereditary human pathologies or disease susceptibilities. To start with the latter, an early report on rs4798571 associating with multiple_sclerosis could not be replicated (Varade et_al, 2012) but a study aimed at identifying genetic factors influencing interferon . . .

     

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