Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ros/ampk signaling pathway

HIGHLIGHTS

  • who: Chang-feng Song from the (UNIVERSITY) have published the article: Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway, in the Journal: (JOURNAL)
  • what: The authors investigated the role of autophagy in Herinduced cell death in pancreatic cancer and showed that Her promoted ROS production and induced autophagic death. This study provides powerful evidence for the development of Her as a therapeutic agent for pancreatic cancer.
  • how: The following antibodies were obtained from Abclonal Technology (Wuhan China) ATG5 (1000 #A0203) AMPKu03b1 (11000 #A12718 . . .

     

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