Heterogeneity and architecture of pathological prion protein assemblies: time to revisit the molecular basis of the prion replication process?

HIGHLIGHTS

• who: Angélique Igel-Egalon and collaborators from the Laboratory of Physical Chemistry (LCP), UMR , CNRS, Université Paris Sud, Orsay, France have published the article: Heterogeneity and Architecture of Pathological Prion Protein Assemblies: Time to Revisit the Molecular Basis of the Prion Replication Process?, in the Journal: (JOURNAL)
• what: The second part of the review reports on the identification of a PrP elementary brick from extractive PrPSc assemblies by methods coupling SV with unfolding/refolding process. In the direct continuity of this work, the authors showed that the kinetic of suPrPU to rfPrP refolding is . . .
  

   

  

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