Heterogeneity of small-cell

HIGHLIGHTS

  • who: Alessandro Morabito and collaborators from the Department of Oncology, Istituto Superiore di Sanità, Viale Regina Elena, Rome, Italy have published the Article: Heterogeneity of Small-Cell, in the Journal: Onco 2022, 2, 186-243. of /2022/
  • what: This study showed that a sensitive NGS assay can be performed on formalin fixed paraffin-enbibed biopsies of SCLC patients . Hu et_al have performed a comprehensive genomic analysis in 122 Chinese SCLC patients by NGS; this analysis showed that: the most frequently altered genes were TP53 (93%), RB1 (79%), LRP1B (19%), KTM2D (16%), FAT1 (11.5%), KTM2C . . .

     

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