Hierarchical coarse-grained strategy for macromolecular self-assembly: application to hepatitis b virus-like particles

HIGHLIGHTS

  • who: Philipp Nicolas Depta and colleagues from the Institute of Solids Process Engineering and Particle Technology (SPE), Hamburg University of Technology, Hamburg, Germany have published the research: Hierarchical Coarse-Grained Strategy for Macromolecular Self-Assembly: Application to Hepatitis B Virus-Like Particles, in the Journal: (JOURNAL) of 14/Nov/2022
  • what: The authors demonstrate that VLP self-assembly phenomena and dependencies are now possible to be simulated. The authors focus on deriving a generally applicable approach for intermolecular interaction potentials (U) between the beads through data-driven fields (6D), on which a gradient operation (-u2207U . . .

     

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