Hif-phd inhibitor regulates the function of group2 innate lymphoid cells and polarization of m2 macrophages

HIGHLIGHTS

• who: Ryuichi Nagashima from the DepartmentShowa University have published the Article: HIF-PHD inhibitor regulates the function of group2 innate lymphoid cells and polarization of M2 macrophages, in the Journal: Scientific Reports Scientific Reports
• what: The authors demonstrated that HIF activation by HIF-PHD inhibitors affected kidney ILC2s and altered their functions.
• how: These results indicated that HIF-PHD inhibition dampened cytokine production of IL-5 and IL-13 but not IL-4 from kidney ILC2s. In fact the results showed that neither IL-2/7 nor IL-2/7/33 stimulation could . . .
  

   

  

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