High aspect ratio nanomaterial-induced macrophage polarization is mediated by changes in mirna levels

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  • who: Johanna Samulin Erdem et al. from the United States Washington University in StLouis have published the Article: High aspect ratio nanomaterial-induced macrophage polarization is mediated by changes in miRNA levels, in the Journal: (JOURNAL)
  • what: In agreement, this study showed that the long and rigid NM-401 fibers gave more severe effects on macrophage markers, as illustrated by increased M2 markers Arg1, Ear11, and Mrc1, and cytokine secretion, compared to the shorter and more coiled NM-400 . The authors demonstrate that the enhanced M1 phenotype observed after CNF exposure did not involve histone . . .

     

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