High-definition transcranial direct current stimulation (hd-tdcs) in major depressive disorder with anxious distress—a study protocol for a double-blinded randomized sham-controlled trial

HIGHLIGHTS

• What: The current randomized controlled trial aims to assess the efficacy of HD-tDCS as an augmentation therapy with antidepressants compared to sham-control in subjects of MDD with ADS. From the pilot study Advantages of a new format of tDCS: HD‑tDCS This study proposes a RCT with parallel group design, in which participants are randomly allocated to the experimental group or the sham group in a 1:1 ratio. The group will meet on a monthly basis to assess progress and ensure that the study is being conducted in accordance with the requirements of research . . .
  

   

  

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