HIGHLIGHTS
- who: Gian-Andri Thun from the Barcelona Institute University Munich Poland have published the Article: High degree of polyclonality hinders somatic mutation calling in lung brush samples of COPD cases and controls, in the Journal: Scientific Reports Scientific Reports of 11/01/2019
SUMMARY
The cellular material of bronchial brushings represented an area of ≈9 cm2 of the airways and contained over 90% airway epithelial_cells. Rather than independently calling variants in affected and reference tissue against a reference genome, all three tools process the sequencing data of the two given tissues simultaneously and . . .
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