High dose osimertinib in patients with advanced stage egfr exon 20 mutation-positive nsclc: results from the phase 2 multicenter position20 trial

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• who: Fenneke Zwierenga from the Department of Pulmonary Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands have published the article: High dose osimertinib in patients with advanced stage EGFR exon 20 mutation-positive NSCLC: Results from the phase 2 multicenter POSITION20 trial, in the Journal: (JOURNAL)
• what: The primary reason for discon­ tinuation was progressive disease in 14 patients (56%). The study showed an objective response rate (ORR) of 24% and a disease control rate (DCR) of 85% , in which the responders all harbored an EGFRex20 + mutation in the loop following C . . .
  

   

  

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