High-efficiency generation of induced pluripotent mesenchymal stem cells from human dermal fibroblasts using recombinant proteins

HIGHLIGHTS

  • who: Fanfan Chen from the Shanghai RandD Center, New England have published the research work: High-efficiency generation of induced pluripotent mesenchymal stem cells from human dermal fibroblasts using recombinant proteins, in the Journal: (JOURNAL)
  • what: The authors demonstrate a novel method using an inactivated viral pArticle to package and deliver four purified recombinant Yamanaka transcription factors (Sox2 Oct4 Klf4 and c-Myc) resulting in reprogramming of human primary fibroblasts. The authors demonstrate improved reprogramming of somatic_cells using a different approach from previous methodologies .

SUMMARY

    Induced pluripotent stem_cells (iPSCs) are somatic_cells . . .

     

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