High expression of b4galt1 is associated with poor prognosis in acute myeloid leukemia

HIGHLIGHTS

  • who: GALT et al. from the Harvard University, United States have published the research: High expression of B4GALT1 is associated with poor prognosis in acute myeloid leukemia, in the Journal: (JOURNAL)
  • what: The study shows that B4GALT1 plays a critical role in the carcinogenesis and progression of LAML, and it may be used as a biomarker to predict patient survival.
  • how: The results showed that overexpression of B4GALT1 was significantly and positively associated with unfavorable cytogenetic risk (dominance ratio 0.256 p=0.002) and NPM1 mutation (OR 2.777 p=0.015 . . .

     

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