High fat diet induces kidney injury via stimulating wnt/β-catenin signaling

HIGHLIGHTS

• who: Chen Yu and Youhua Liu from the Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States, Department of have published the paper: High Fat Diet Induces Kidney Injury via Stimulating Wnt/u03b2-Catenin Signaling, in the Journal: (JOURNAL)
• what: This study shows a series of metabolic alterations in HFD mice, including weight gain, elevated blood glucose, and accumulation of lipid droplets in the liver and kidney. Most importantly, the authors show for the first time that Wnt/u03b2-catenin signaling plays a pivotal role in mediating obesity-associated kidney injury . . .
  

   

  

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