High-fat diets enhance and delay ursodeoxycholic acid absorption but elevate circulating hydrophobic bile salts

HIGHLIGHTS

  • who: April and collaborators from the Gilead, United States University of Toyama, Japan have published the research work: High-fat diets enhance and delay ursodeoxycholic acid absorption but elevate circulating hydrophobic bile salts, in the Journal: (JOURNAL)

SUMMARY

    Endogenous bile_salts (Crosignani et_al, 1996). The absorption of UDCA is usually incomplete because the gastrointestinal fluid is not alkaline enough to dissolve the clinical dose (Parquet et_al, 1985; Stiehl et_al, 1988). Gut flora participates in the disposition of UDCA as bile_salts undergo extensive host-gut microbial co-metabolism (Ridlon et_al, 2016). Longterm treatment of UDCA . . .

     

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