High fluoroquinolone resistance proportions among multidrug-resistant tuberculosis driven by dominant l2

HIGHLIGHTS

• who: Viola Dreyer from the Borstel, Germany have published the article: High fluoroquinolone resistance proportions among multidrug-resistant tuberculosis driven by dominant L2, in the Journal: (JOURNAL)
• what: Our data indicate that the pre-XDR/ XDR-TB epidemic can be propelled by few clones with high proportions of pre-existing drug resistances and ongoing selection for compensatory mutations, virulence determinants, and resistances against new drugs and drugs of last resort.
• how: Genome analysis All WGS data were analyzed using the MTBseq pipeline (Version 1.0.3) . In a first step the authors compared . . .
  

   

  

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