High-frequency stimulation of the subthalamic nucleus induces a sustained inhibition of serotonergic system via loss of cell phenotype

HIGHLIGHTS

  • who: Faisal Alosaimi from the DepartmentMaastricht University have published the Article: High-frequency stimulation of the subthalamic nucleus induces a sustained inhibition of serotonergic system via loss of cell phenotype, in the Journal: Scientific Reports Scientific Reports
  • what: The authors investigated the neuroplastic effects of DBS on neurotransmitter phenotype.
  • how: Behavioral and immunohistochemical data were analyzed using two-way ANOVA.

SUMMARY

    Understanding the neuronal mechanisms of these behavioral changes is relevant for the more than 208,000 patients that are already treated by DBS w ­ orldwide20. MPTP administration in . . .

     

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