High glucose-induced inhibition of osteoblast like mc3t3-e1 differentiation promotes mitochondrial perturbations

HIGHLIGHTS

• who: Claudia Medeiros and Joseph M. Wallace from the Department of Biomedical Engineering, Indiana University-Purdue Indianapolis (IUPUI), Indianapolis have published the research: High glucose-induced inhibition of osteoblast like MC3T3-E1 differentiation promotes mitochondrial perturbations, in the Journal: PLOS ONE of 29/03/2022
• what: To bridge the gap between T2D and bone disorders, the authors aim to determine expression and function of key TCA enzymes, cellular respiration, and fuel oxidation. Because previous work examined mitochondrial genes associated with OXPHOS Glucose-induced mitochondrial dysfunction in MC3T3 cells and mitochondrial fission and fusion, the focus . . .
  

   

  

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