High glucose-induced kidney injury via activation of necroptosis in diabetic kidney disease

HIGHLIGHTS

  • who: Man Guo and colleagues from the Department of Endocrinology and Metabolism, The Affiliated Hospital of Southwest Medical University, Luzhou, China have published the research: High Glucose-Induced Kidney Injury via Activation of Necroptosis in Diabetic Kidney Disease, in the Journal: Oxidative Medicine and Cellular Longevity of 30/01/2023
  • what: The authors focused on the necroptosis of renal tubules Pathophysiology in DKD Mice.
  • how: The study is the first to show that blocking RIPK1 by Nec-1 ameliorates renal dysfunction and reduces kidney inflammation in DKD.
  • future: While the research . . .

     

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