HIGHLIGHTS
- who: Andrew N. Murtha et al. from the Editor: SWeiss, Emory University School of Rennes, France, Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, United States have published the paper: High-level carbapenem tolerance requires antibiotic-induced outer membrane modifications, in the Journal: (JOURNAL)
- what: The authors used Enterobacter cloacae as a model Gram-negative pathogen to investigate genetic factors that contribute to bacterial tolerance to meropenem, which is used as a last-resort β-lactam to treat multidrug-resistant bacterial infections . The authors propose that lipid A molecules with a positive charge increase outer PLOS . . .
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