High-level de novo biosynthesis of glycosylated zeaxanthin and astaxanthin in escherichia coli

HIGHLIGHTS

  • who: Xixian Chen from the (UNIVERSITY) have published the Article: High-level de novo biosynthesis of glycosylated zeaxanthin and astaxanthin in Escherichia coli, in the Journal: (JOURNAL)
  • what: The authors report metabolic engineering efforts (e_g promoter and RBS engineering optimization of carbon sources and supplementation of bottleneck genes) to produce glycosylated carotenoids in Escherichia coli. The work demonstrated a proof-of-concept study for the microbial biosynthesis of glycosylated carotenoids.
  • how: The authors hypothesized that glycosylation of zeaxanthin could be limited by insufficient A C B activity of ZGT.

SUMMARY

     

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