High-level mycn-amplified rb1-proficient retinoblastoma tumors retain distinct molecular signatures

HIGHLIGHTS

  • who: Khashayar Roohollahi MSc from the Patient Material and Characteristics Retinoblastoma tumor material was previously collected [9, ]In brief, patient samples were collected after primary enucleation, before start of other treatments at the Amsterdam University Medical Center (UMC) and immediately frozen in liquid nitrogen and stored at e, have published the article: High-Level MYCN-Amplified RB1-Proficient Retinoblastoma Tumors Retain Distinct Molecular Signatures, in the Journal: (JOURNAL) of June/13,/2022
  • what: The analysis showed a significant negative correlation between mean expression of the MYCNA RB1PRO signature genes and the expression of MYCN (R . . .

     

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