High level of susceptibility to human trim5 α conferred by hiv-2 capsid sequences

HIGHLIGHTS

  • who: Takeuchi et_al Retrovirology et al. from the (UNIVERSITY) have published the research work: High level of susceptibility to human TRIM5 α conferred by HIV-2 capsid sequences, in the Journal: (JOURNAL) of 12/04/2013
  • what: The authors have examined the antiviral activity of hTRIM5α on recombinant viruses expressing a wide panel of HIV-2 CA proteins directly amplified from the plasma of infected patients. The authors provide strong evidence, however, that these viruses produced a capsid structure that is biologically relevant to that of full length HIV-2. The study provides further evidence that . . .

     

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