High levels of cerebrospinal fluid kappa free light chains relate to igm intrathecal synthesis and might have prognostic implications in relapsing multiple sclerosis

HIGHLIGHTS

• who: Jéssica Castillo-Villalba from the University of Gothenburg, Sweden United States have published the article: High Levels of Cerebrospinal Fluid Kappa Free Light Chains Relate to IgM Intrathecal Synthesis and Might Have Prognostic Implications in Relapsing Multiple Sclerosis, in the Journal: (JOURNAL) of 02/Dec/2021
• what: This work indicates a potential link between KFLC, OCMBs, and eLFs and suggests an added prognostic value for KFLC measurement.
• how: The authors compared time to Expanded Disability Status Scale (EDSS) 3 and to initiation of highefficacy disease-modifying therapies (heDMTs) by multivariate Cox . . .
  

   

  

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