High-progesterone environment preserves t cell competency by evading glucocorticoid effects on immune regulation

HIGHLIGHTS

  • who: Hirofumi Kashiwagi from the Faculty of Medical Sciences, Wuhan University, China have published the paper: High-progesterone environment preserves T cell competency by evading glucocorticoid effects on immune regulation, in the Journal: (JOURNAL)
  • what: The authors aimed to comprehensively compare the effects of P4 and COR on human lymphocytes in_vitro and in_vivo to clarify their role in the systemic regulation of immunity during pregnancy. Because the authors aimed to compare the APC-involved T_cell response in the presence of steroids, the authors selected one of such superantigens, TSST-1 for in_vitro stimulation of T_cells . . .

     

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