HIGHLIGHTS
SUMMARY
Parkinson`s disease (PD) is the second common aging-related central neurodegenerative disease with different types of motor and non-motor symptoms. In 2012, Manson et_al3 reviewed studies of the incidence of dyskinesia in PD patients. As one of the most disabling motor complications in PD patients, dyskinesia imposes a huge burden on the patients, their family, and society4. The clinical manifestations of dyskinesia can be divided into three main patterns, including peak-dose dyskinesia, "off" dyskinesia, and biphasic dyskinesia6, with peak-dose dyskinesia being the most common in PD. An in_vivo study also . . .

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