HIGHLIGHTS
- who: Manchi C. M. Reddy from the Department of Biochemistry and Biophysics, Texas A and M University, College Station, Texas , have published the research: High Resolution Crystal Structures of Mycobacterium tuberculosis Adenosine Kinase, in the Journal: (JOURNAL) of SEPTEMBER/14,/2007
SUMMARY
The negatively charged O-5⬘ atom immediately adjacent to the ␥-phosphate of the ATP is one of_(at 2.6 Å from the OD-2 Asp257) could then make a waterthe structural requirements for the reaction mechanism (40, mediated (W-1) nucleophilic attack on the ␥-phosphate of 41). The resulting charge difference . . .
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