High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer

HIGHLIGHTS

  • who: Stefan Salcher from the Department Medical University of Innsbruck, Innsbruck, Austria have published the article: High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer, in the Journal: (JOURNAL) of December/12,/2022
  • what: The authors show that a TRN-derived gene signature is associated with anti-programmed cell death ligand 1 (PD-L1) treatment failure. TRNs acquire new properties in the TME One unique feature of the large-scale NSCLC atlas the authors assembled is the enrichment with single-cell expression profiles from neutrophils . . .

     

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