High-resolution tads reveal dna sequences underlying genome organization in flies

HIGHLIGHTS

• who: Fidel Ramírez from the Faculty University of, Freiburg, Germany have published the research work: High-resolution TADs reveal DNA sequences underlying genome organization in flies, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 26/06/2017
• what: The authors develop software (HiCExplorer) to obtain boundary positions at 0.5 kilobase resolution based on published Hi-C sequencing data from Drosophila melanogaster Kc167 cell line15,16. The analysis showed that Beaf-32 and M1BP motifs are enriched at Drosophila boundaries. The authors show that correlating boundaries with ChIP-Seq peaks alone is not a . . .
  

   

  

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