High-resolution transcriptomic and proteomic profiling of heterogeneity of brain-derived microglia in multiple sclerosis

HIGHLIGHTS

  • who: Susanne M. Kooistra from the Section Molecular Neurobiology, Department of Biomedical Sciences of Cells and Systems, University Medical Center University of Lausanne, Switzerland have published the research work: High-Resolution Transcriptomic and Proteomic Profiling of Heterogeneity of Brain-Derived Microglia in Multiple Sclerosis, in the Journal: (JOURNAL)
  • what: The authors focus on WM/GM microglial heterogeneity and microglial differences between species and sex (summarized in Figure 2). microglia/macrophages that form a rim around the lesion could impair the remyelination process, resulting in slowly expanding lesions rather than shrinkage of the lesion. HETEROGENEITY OF . . .

     

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