High-throughput drug screening identifies fluoxetine as a potential therapeutic agent for neuroendocrine prostate cancer

HIGHLIGHTS

  • who: Lei Chen and collaborators from the American University of Beirut, Lebanon United States have published the paper: High-throughput drug screening identifies fluoxetine as a potential therapeutic agent for neuroendocrine prostate cancer, in the Journal: (JOURNAL)
  • how: The authors carried out both in_vitro and in_vivo experiments to demonstrate the inhibitory effects of fluoxetine on NEPC models and its mechanism in detail. The authors conducted western blot analysis to confirm the inhibitory effect of fluoxetine on the PI3K-AKT pathway.

SUMMARY

    The authors carried out both in_vitro and in_vivo experiments to . . .

     

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