High-throughput quantitative binding analysis of dna aptamers using exonucleases

HIGHLIGHTS

  • who: Juan Canoura et al. from the Department of Chemistry, North Carolina State University, Yarbrough Drive, Raleigh, NC, USA and Department of Chemistry and Biochemistry, Florida International University, SW, th Street, Miami, FL, USA have published the article: High-throughput quantitative binding analysis of DNA aptamers using exonucleases, in the Journal: (JOURNAL)
  • what: The authors demonstrate the utility of this approach by isolating a set of new aptamers for fentanyl and its analogs and then characterizing the binding properties of 655 aptamer-ligand pairs using the exonuclease digestion assay and validating the results with gold . . .

     

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