High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating cd8+/regulatory t-cell infiltration

HIGHLIGHTS

• who: Sehui Kim from the Department of Pathology, Seoul National University College of Medicine, Daehaku2011ro, Jongnou2011gu, Seoul, Republic of Korea have published the research work: High tumor hexokinase-2 expression promotes a pro-tumorigenic immune microenvironment by modulating CD8+/regulatory T-cell infiltration, in the Journal: (JOURNAL)
• what: This study demonstrated that tumor HK2 expression/glycolysis can influence the immune profile of the TME, and an increase in tumor HK2 expression/glycolysis might be linked to a decreased CD8 + T-cell to Treg ratio, implying a poor prognosis.
• how: Data were analyzed using . . .
  

   

  

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