Higher cerebrospinal fluid biomarkers of neuronal injury in hiv-associated neurocognitive impairment

HIGHLIGHTS

• who: Ronald J. Ellis from the Laboratory evaluations HIV disease was diagnosed by enzyme-linked immunosorbent assay with Western blot confirmationHIV RNA in plasma was measured using commercial assays and deemed undetectable at a lower limit of , copies/ml. , T cells were measured by flow cytometry and nadir , by self-report. CSF was collected in polypropylene tubes as previously described to minimize protein adsorption (Vanderstichele et_al, ) and stored at , u00b0C. Samples were thawed on the day of analysis, centrifuged at, u00d7 g for , min, and plated in Quanterix-supplied, well plates. The fully automated Simoa platform (www . . .
  

   

  

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