Higher-order oligomerization targets plasma membrane proteins and hiv gag to exosomes

HIGHLIGHTS

• who: PLoS BIOLOGY et al. from the DepartmentHopkins University have published the research: Higher-Order Oligomerization Targets Plasma Membrane Proteins and HIV Gag to Exosomes, in the Journal: (JOURNAL)
• what: The authors provide evidence that both the HIV late domain and class E VPS function promote HIV budding by unexpectedly complex seemingly indirect mechanisms. The authors show that higher-order oligomerization and plasma membrane association target proteins to sites of exosome budding and into exosomes. The authors show here that p6-deficient HIV can bud from cells at normal levels and that both p6-deficient . . .
  

   

  

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