Highly efficient hybridoma generation and screening strategy for anti-pd-1 monoclonal antibody development

HIGHLIGHTS

  • who: Tanapati Phakham from the Chulalongkorn University Bangkok, Thailand have published the research: Highly efficient hybridoma generation and screening strategy for anti-PD-1 monoclonal antibody development, in the Journal: Scientific Reports Scientific Reports
  • what: The authors demonstrated a highly efficient strategy for generating, screening, and characterizing chimeric anti-PD-1 antibodies; see the workflow in Fig 1. This study shows the details of the hybridoma generation, selection, and screening procedure to successfully develop high-potency chimeric anti-PD-1 mAbs for cancer immunotherapy. Collectively, although each of the technique employed for the hybridoma generation . . .

     

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