Highly sensitive characterization of non-human glycan structures of monoclonal antibody drugs utilizing tandem mass spectrometry

HIGHLIGHTS

  • who: Yi-Min She from the Centre have published the research: Highly sensitive characterization of non-human glycan structures of monoclonal antibody drugs utilizing tandem mass spectrometry, in the Journal: Scientific Reports Scientific Reports
  • what: The authors propose that the digalactosylated structure (Fig 2c) contains an u03b1-Gal-Gal-GlcNAc-Man branch, as indicated by the presence of the two diagnostic ions at m/z 528.14 ([u03b1-Gal-Gal-GlcNAc + u00adH]+) and m/z 690.22 ([u03b1-Gal-Gal-GlcNAcMan + u00adH]+), and the intensity of the former fragment is higher than that of the . . .

     

    Logo ScioWire Beta black

    If you want to have access to all the content you need to log in!

    Thanks :)

    If you don't have an account, you can create one here.

     

Scroll to Top

Add A Knowledge Base Question !

+ = Verify Human or Spambot ?